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Category Archives: cancer news

Optimal Cancer Therapy

For optimal cancer therapy, it would be important to know which genes in cancer cells have altered in the patients. In the largest cancer genome study of its kind now, American doctors have sequenced the genomes of tumors from 50 breast cancer patients and compared with the DNA sequences of healthy cells of the same patient.

Surprisingly, the researchers found only a few mutations that occurred with greater frequency. Instead, the varied nature of the mutations between the patients very much. Regardless, the pending analysis of DNA sequences provide important information for better, individual therapy, the scientists said at the annual meeting of the American Association for Cancer Research in Orlando. “Cancer genomes are extremely complicated. This explains the difficulty to predict the treatment outcome and to develop new treatments,” says Matthew Ellis of Washington University in St. Louis, one of the leaders of the project.

Overall, the researchers found more than 1700 mutations. However, most of which came to only one patient. In addition to two known mutations that are present in 40 or 20 percent of cases, researchers identified only three other, previously unknown mutations that were detectable at least ten percent of the tumors. And 21 more altered genes occurred in only two to three patients.

All tumors in the study were estrogen receptor-positive, meaning their growth was strongly stimulated by estrogen. Nevertheless, only in half of cases, effective cancer drug that blocked the estrogen effect. It is not known why the anti-hormonal therapy is effective in some estrogen receptor-positive cancers, and not for others. Detailed analysis of sequence data now available to help you find the cause.

The cancer genome research is an important step towards personalized medicine. It is routinely the tumor genome of the patients are sequenced in the not too distant future after a cancer diagnosis, so that a possible to this type of cancer tailored, optimal therapy.

 
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Posted by on April 4, 2011 in cancer news

 

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SPAIN, third largest SMOKERS

SPAIN, third largest SMOKERS


“In fact, until 2000, Spain was at the bottom of Europe in the number of women smokers, but now ranks third.|

In this sense, experts say that the high prevalence should be a compelling reason, not only to enhance smoking cessation plans, regardless of gender, but also to urge the government to achieve greater political commitment to cancer research In order to find new treatments that achieve a cure or improve survival and quality of life of patients.

In his opinion, further steps should target the development of innovation aimed at the definition of clinical criteria and molecular imaging that can identify individuals with higher risk of lung cancer, the development of screening programs as efficient as possible and research of new molecules which may play a role in this struggle.

 
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Posted by on March 3, 2011 in cancer news

 

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cancer mortality is declining 1% per year

The main oncologists Spain stressed yesterday that the cancer mortality is declining 1% per year since 2000 and that investments are acceptable, but considered that further resources and assistance to the sick has considerable shortcomings with the low number of specialists, which forces them to reduce the “time care to an extent unacceptable. ” He estimates that Spain would need to raise the specialists in almost one third to 23 per million inhabitants (about 1,008). The national health system now has only 15 per million population (705).


The Foundation for Excellence and Quality Oncology (ECO), formed by 23 department heads of the main Spanish hospitals, estimated that by 2015 there will be in Spain 220,000 new cases of cancer and is expected that one in four people suffer the disease at some point in their lives. It is estimated that today in Spain about 1.5 million people may have cancer. According to Rafael L√≥pez, head of the Clinical Hospital of Santiago de Compostela, the “increased workload”, and the shortage of specialist, joins the “poor” oncologic training taught in Spanish universities and the need to move towards a “more humanized medicine. “

 
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Posted by on February 23, 2011 in cancer news

 

Breastfeeding Can Help Protect Children In The Future From Cancer

About 60% of births in Armenia are currently breastfeeding, said Head of the Department of Maternal and Child Health Ministry of Health Karine Saribekian.


“According to 1994 in Armenia, about 20%, ie 20 out of 100 children, were breastfed for up to four months. Over the next three or four years, the number of such children has tripled and even quadrupled. After this index again fell slightly. Currently, about 60% of births in Armenia are breastfed, “- said Saribekian on Thursday at the parliamentary hearings on the issue of breast-feeding children in Armenia.


According to the head of department, breast-feeding not only helps to strengthen the health of both mother and child, but also creates a strong emotional bond between them.


As noted Saribekian, interesting practice doctors apply to women who want to abandon their children in the hospital. “They just give us feed the baby. After that, the vast majority of women take their children “- she said.


As informed Saribekyan, with mother’s milk the child absorbs and information stored at the level of genes. That is why, as stressed by the representative of the Ministry of Health of Armenia, should be encouraged breastfeeding at least six months.


Chairman of the Standing Committee on Health, Maternity and Childhood Ara Babloyan said that breastfeeding can help protect children in the future from such diseases as diabetes, cancer, and the mothers will prevent breast cancer  and ovarian cancer.


“Breastfeeding could save lives of millions of children around the world” – said Babloyan.

 
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Posted by on February 18, 2011 in cancer news

 

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Smoking Are No The Only Lung Cancer Triggerer

Lung cancer triggers not only because of smoking. A number of carcinogenic substances such as asbestos, arsenic, chromate, nickel, chloromethyl ether, radiation, and pollution also can cause lung cancer.


About 90 percent of cases of lung cancer in men and 70 percent in women are due to smoking habits. The more smoke of cigarettes enter the lung, the greater the risk for lung cancer. The cause is because tobacco smoke contains over 4,000 chemicals, and most are carcinogenic and cause cancer.


Two major carcinogenic substances in cigarette tobacco are nitrosamines and polycyclic aromatic hydrocarbons. However, cigarette is not the only cause of lung cancer.

Many who inhaled substances in the workplace which are carcinogenic. For example, asbestos, arsenic, chromate, nickel, chloromethyl ethers, mustard gas, and coke oven emission and radiation can cause lung cancer.

 
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Posted by on January 20, 2011 in cancer news

 

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Soy against 2 cancer, prostate and breast cancer

In addition to flavor our food, soy may also help in the battle against two types of cancer: the breast and the prostate. To detect the two studies were reported by British newspaper the Daily Mail. The first ‘was conducted by a team of researchers at the University of Chicago Northwestern. The results ‘showed that one pill a day of’ genistein ‘, the main isoflavone found in soy, and’ able to slow or stop the spread of prostate cancer.


Although the study involved a small sample of 38 men, scientists believe that these results could lead to the first non-toxic treatment that prevents the movement of cancer cells.

“The first step – said Raymond Bergan, who led the study – and ‘was to see if the drug has the desired effect on the cells and the prostate, and the answer’ it was ‘. If this drug can’ effectively prevent prostate cancer can spread throughout the body, such therapy could theoretically have the same effect on the cells of other types of cancer. “


The second study ‘pro-soy’ and ‘was conducted by the University’ of Buffalo (New York) and involved nearly 1,300 women. The results’ showed that soy isoflavones may reduce the risk of developing breast cancer. Researchers have found that women who consumed more ‘isoflavones have a 30 percent chance’ to be less affected by invasive breast cancer and 60 per cent chance ‘in less than developing cancer’ low degree ‘.


To arrive at these conclusions, the scientists compared the data of 683 women with breast cancer with 611 healthy women. “We have definitely seen – said Anne Weaver, who led the study – a reduction (risk) that deserves further investigation.”

 
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Posted by on January 17, 2011 in cancer news

 

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Zafgen diet pills originally developed to treat solid tumors in cancer cases

The active ingredient used in the diet pill of Zafgen (ZGN, 433) was originally developed by a South Korean pharmaceutical (CKD Pharmaceuticals) to treat solid tumors in cancer cases. It works by increasing the breakdown of fat. Zafgen CKD Pharmaceuticals has bought the exclusive rights to use ZGN-433 in the world (except South Korea).


Various scientific studies have suggested that the more overweight you become, the more your body will struggle to change its composition because the body becomes “programmed” to produce and store more fat. This makes the body less sensitive to the insulin hormone (a hormone that helps us to fight against excess weight because it encourages the body to burn fat). 


The researchers say that the Zafgen ZGN-433 diet pill blocks an enzyme called MetAP2. This enzyme is harmful because it prevents many genes that are important to function properly. This enzyme MetAP2 indirectly promotes insulin resistance, excessive fat, inflammation, various health problems related to obesity. In fact, scientists believe their Zafgen drug works because it resets the way the body metabolizes fat.

 
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Posted by on January 16, 2011 in cancer news

 

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