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Breast Cancer More Aggressive On Overweight Women

More likely to relapse after treatment, a poorer prognosis … breast cancers are more aggressive among overweight women, but until then we can explain it. But two French research teams are to elucidate this mystery.

In addition to these deleterious effects on cardiovascular health and the onset of diabetes, obesity may play a role in the prognosis of breast cancer, especially its ability to spread to other organs. This statistical relationship is to find a physiological explanation by two research teams bringing together researchers from INSERM, CNRS and Université Paul Sabatier.

An interaction between adipocytes and breast tumor
The outer part of the breast is mainly composed of fatty tissue, itself largely composed of adipocytes. These cells are capable, in addition to their storage / release of fat to secrete many proteins. The researchers investigated whether these proteins play a role in the development of breast cancer.

To do this, teams Philippe Valet at the Institute of metabolic and cardiovascular diseases (Inserm / Université Paul Sabatier) and Catherine Muller at the Institute of Pharmacology and Structural Biology (CNRS / Université Paul Sabatier) cells were grown together mammary tumor and adipocytes.

In the presence of tumor cells, adipocytes change and show a change in the secretion of some of their proteins, including inflammatory proteins such as interleukin 6. Gradually, these cells establish effective interaction with the tumor, which leads to an increase in its “colonization potential”, so its aggressiveness.

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Posted by on April 10, 2011 in Breast Cancer

 

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Breastfeeding Can Help Protect Children In The Future From Cancer

About 60% of births in Armenia are currently breastfeeding, said Head of the Department of Maternal and Child Health Ministry of Health Karine Saribekian.


“According to 1994 in Armenia, about 20%, ie 20 out of 100 children, were breastfed for up to four months. Over the next three or four years, the number of such children has tripled and even quadrupled. After this index again fell slightly. Currently, about 60% of births in Armenia are breastfed, “- said Saribekian on Thursday at the parliamentary hearings on the issue of breast-feeding children in Armenia.


According to the head of department, breast-feeding not only helps to strengthen the health of both mother and child, but also creates a strong emotional bond between them.


As noted Saribekian, interesting practice doctors apply to women who want to abandon their children in the hospital. “They just give us feed the baby. After that, the vast majority of women take their children “- she said.


As informed Saribekyan, with mother’s milk the child absorbs and information stored at the level of genes. That is why, as stressed by the representative of the Ministry of Health of Armenia, should be encouraged breastfeeding at least six months.


Chairman of the Standing Committee on Health, Maternity and Childhood Ara Babloyan said that breastfeeding can help protect children in the future from such diseases as diabetes, cancer, and the mothers will prevent breast cancer  and ovarian cancer.


“Breastfeeding could save lives of millions of children around the world” – said Babloyan.

 
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Posted by on February 18, 2011 in cancer news

 

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