Tag Archives: cancer

Zafgen diet pills originally developed to treat solid tumors in cancer cases

The active ingredient used in the diet pill of Zafgen (ZGN, 433) was originally developed by a South Korean pharmaceutical (CKD Pharmaceuticals) to treat solid tumors in cancer cases. It works by increasing the breakdown of fat. Zafgen CKD Pharmaceuticals has bought the exclusive rights to use ZGN-433 in the world (except South Korea).

Various scientific studies have suggested that the more overweight you become, the more your body will struggle to change its composition because the body becomes “programmed” to produce and store more fat. This makes the body less sensitive to the insulin hormone (a hormone that helps us to fight against excess weight because it encourages the body to burn fat). 

The researchers say that the Zafgen ZGN-433 diet pill blocks an enzyme called MetAP2. This enzyme is harmful because it prevents many genes that are important to function properly. This enzyme MetAP2 indirectly promotes insulin resistance, excessive fat, inflammation, various health problems related to obesity. In fact, scientists believe their Zafgen drug works because it resets the way the body metabolizes fat.

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Posted by on January 16, 2011 in cancer news


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Decrease Your Risk Of Cancer With Green Tea


The majority people are frightened rigid of cancer disease. That is fairly reasonable – nobody wants to waste a couple of years having chemotherapy just to pass away a few years later? Or yet if you get well it is a couple of years out of your existence that have been upsetting and punishing. And not just for the patient but for associates and family too.

So, most people do the whole lot they capable of to decrease the risks of developing cancer. Many of us don’t think we recognize how to do this, while other people are not certain, but they have listened to or read a bit that sounds ‘about right’ and other people are assured that they know how to avoid having cancer.

My relatives are persuaded that I might obtain cancer from consumption of burnt toast and others are convinced that they can ward off cancer by saturating their flesh with green tea. It has frequently been said out and for decades too, that countries where green tea is the norm, say the Far East, have a large amount of lower occurrence of cancer than we do in the West.

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Posted by on January 9, 2011 in cancer news


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Aretha Franklin Dies Of Pancreatic Cancer

Another hoax news reporting Aretha Franklin’s death from the out of control internet world these days.

The gossips circulating that poor soul singer Aretha Franklin, she has the hat size of the satellite has recently been treated for cancer of the pancreas notoriously rough.

Twitter rumors have multiplied that the 68-year-old singer died from the disease, and history will pull through retweet generally useful function that users clicked the retweet compassion ultimately useless.

From now on, there is no reason to believe Franklin is dead or is a new danger to do so in the near future. CNN correspondent Roland S. Martin denied the rumor on his Twitter account, they shout people and re-tweet tweet misinformation that Aretha is not dead because of pancreatic cancer.

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Posted by on December 28, 2010 in cancer news


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Smoking ups death risk due to breast cancer

A new study has revealed the women who smoke or have a history of smoking are at 39 percent higher risk of death due to breast cancer.

Although smoking is associated with lung cancer and implicated in several other cancers, it is unclear what effect smoking has on breast cancer, said Dejana Braithwaite of the University of California.

“Specifically, it is unclear how long women live following breast cancer diagnosis and whether smoking increases the risk of death because of breast cancer progression or whether there is an association between smoking and life expectancy following breast cancer diagnosis that works through affecting non-breast cancer causes of death,” she said.

Braithwaite and colleagues enrolled 2,265 multi-ethnic women diagnosed with breast cancer between 1997 and 2000. Researchers examined whether smoking affected death from breast cancer, non-breast cancer related causes and death from all causes.

Results showed that 164 deaths from breast cancer and 120 deaths from non-breast cancer causes occurred during follow-up.

Women who were current or past smokers and also had a HER2-negative tumour subtype had a 61 percent increased risk for breast cancer death compared with those who never smoked.

“The implication of this research is that it is important for physicians to improve smoking cessation efforts, especially among women newly diagnosed with breast cancer, in order to improve breast cancer specific outcomes and overall health outcomes,” said Braithwaite.

The findings were presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference.

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Posted by on November 9, 2010 in cancer news


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Michael Douglas battling throat cancer – visiting his son Cameron in prison.

As he battles throat cancer, Michael Douglas remains an upstanding father, visiting his son Cameron in prison.

Douglas rep Allen Burry told E! that the three-hour commute from Manhattan to the jail in Lewisburg, PA, where Cameron resides is draining Douglas as he is “recuperating from the [chemotherapy] process”.

“He’s not going every day and not as often as he would like, but he is still visiting with him,” said Burry.

Douglas recently completed chemotherapy after being diagnosed with stage four throat cancer. His son Cameron, 31, is currently serving a five-year sentence for drug possession and dealing.

Overall, it sounds like Douglas is rebounding per Burry: “Obviously he has to recuperate and is not going to be out dancing soon, but he is recovering nicely and no more [treatments] are scheduled.”

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Posted by on October 30, 2010 in cancer news


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Prostate cancer screening

By Dr. Gino Carpinito, Chairman, Department of Urology, Tufts Medical Center

The Prostate Cancer Education Council recommends that men age 40 and older begin screening for prostate cancer. Men at high risk like African-American men or men with a family history of prostate cancer should begin screening at age 35.

Since the late 1980’s when prostate screening with the PSA began, the 5 year survival rate for men with prostate cancer has risen dramatically from 75% to over 99%.

The prostate gland is a part of the male reproductive system. The prostate is about the size of a walnut and is located below the bladder and in front of the rectum. The prostate surrounds the urethra, the canal that the urine passes through as it moves from the bladder during urination. The main function of the prostate is to produce the liquid part of semen necessary for ejaculation and sperm function.

Prostate cancer is an uncontrolled growth of abnormal cells in the prostate gland. Most prostate cancers usually grow slowly, however some cancers can grow rapidly and spread outside the prostate gland. Prostate cancer usually has no signs or symptoms, especially in its earliest stages. However, once the cancer has grown, it may cause discomfort and a variety of other symptoms.

Below are a few of the many reasons why it is so important to be screened for prostate cancer:
• 1 in 6 American men will get prostate cancer in their lifetime.
• Over 30,000 men will needlessly die of prostate cancer this year alone.
• A man is 33% more likely to get prostate cancer than a woman is to get breast cancer.
• Chances of survival improve substantially with early diagnosis and treatment.
• If diagnosed and treated early, survival rates are nearly 100%.
• The best protection against lethal advanced prostate cancer is early detection.

A digital rectal exam (DRE) performed together with the prostate specific antigen (PSA) blood test is the most effective way to detect prostate cancer at an early and likely curable state. PSA is produced by both normal and cancerous prostate cells and is measured in a blood sample. The higher the PSA level, the greater the chance a man has prostate cancer. Elevated PSA tests are usually followed by an ultrasound and a biopsy to determine whether cancer is present and, if so, its level of development. Both DRE and PSA tests are preformed during prostate cancer screening.

Treatment options depend on the stage of the disease, patient’s age, physician’s recommendation and personal decision. Some prostate cancers may never affect a patient’s health and are better left untreated to avoid potential complications of treatment. Such cancers are managed by a conservative approached known as “Watchful waiting”, when the patient is closely observed by his physician, but no active treatment is undertaken.

The first course of action for treating the disease includes, but is not limited to:
• Surgery (Radical Prostatectomy)
• Radiation Therapy
• Hormone Therapy (Advanced cancer)
• Chemotherapy (Advanced cancer)


Testing for prostate cancer is a personal decision that should be made by each man in consultation with his physician. The advantages of screening were discussed above. Some disadvantages of early detection should be also considered, such as false-positive results. These are infrequent, but cause unnecessary anxiety and have to be ruled out by additional tests such as prostate biopsies. Large research studies are ongoing to study benefits and shortcomings of early prostate cancer detection and treatment.

For an appointment with the Tufts Urology Clinic please call 617/636-6317.

Article funded through the Asian Health Initiative of Tufts Medical Center

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Posted by on October 10, 2009 in cancer news


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Tips for avoiding high risk of pancreatic cancer

Tips for avoiding high risk of pancreatic cancer
Written by: Andy Mac Laughlin

Many everyday items contribute significantly to vulnerability.

With the recent publicity given pancreatic cancer following the tragic death of Patrick Swayze, has posted six ways to protect against the disease.

Among the top five leading cancers in the U.S., people suffering from diabetes, gall bladder disease, celiac disease and liver damage are particularly succeptible. Many household items increase the risk, and their list focuses on items that require note.

(1): Alcohol and hard liquor, which damage the liver and pancreas.

(2): Cigarettes, an environmental trigger for pancreatic cancer among predisposed patients.

(3): Soda, and foods that raise insulin blood levels, as pancreatic cancer is among the many disease risks for people with a high insulin blood level.

(4): Non-stick pots, some experts link these to the chemical PFOA, which has proved cancerous in animal studies.

(5): Soft plastics, many contain phthalates (teething rings, water bottles, etc.) which many research articles link to cancer.

(6): Animal and trans fats, as a study in June 2009 showed a direct relationship between pancreatic cancer and dairy or red-meat derived fats.

The warning is rather frightening, as many of the items are so commonplace. Forewarned is forearmed though, and better awareness may save lives.

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Posted by on September 20, 2009 in cancer news


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